Description
- MK-677 - 25mg per capsule
- 30 Capsules per bottle
MK-677, also known as ibutamoren, is an investigational drug that functions as a growth hormone secretagogue, mimicking the action of ghrelin to stimulate the release of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). Recent research has explored its potential applications.
Recent animal studies have explored the effects of MK-677 (ibutamoren), a growth hormone secretagogue, on various physiological parameters.
Growth Hormone and IGF-1 Levels
In canine studies, repeated oral administration of MK-677 significantly increased serum growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels. This elevation was sustained over the treatment period, indicating MK-677's potential to enhance GH and IGF-1 secretion in dogs.
Cognitive Function and Neuroprotection
In a murine model of Alzheimer's disease (5XFAD mice), MK-677 administration led to a reduction in amyloid-beta accumulation, neurodegeneration, and neuroinflammation. These findings suggest that MK-677 may have neuroprotective effects and could be beneficial in mitigating Alzheimer's-related pathology.
Metabolic Effects
Equine studies have investigated the metabolism of MK-677, revealing its metabolic pathways following oral administration in horses. Understanding these pathways is crucial for assessing the drug's safety and efficacy in equine species.
