Description
Thymosin Beta 4 (TB500)
5mg per vial
| Product Name | Thymosin Beta 4 |
| Unit Size | 5mg per vial |
| CAS No. | 77591-33-4 |
| Synomyms | TB500 |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr- Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH |
| Molecular Formula | C212H350N56O78S |
| Purity | >98% |
| Physical State | Lyophilized Powder |
| Storage | Although lyophilized peptides are stable at room temperature for up to 2 months, they should be stored desiccated below -18°C. On reconstitution, the peptide should then be stored at 4°C |
TB500 or Thymosin Beta 4 plays many important roles including the induction of tissue remodelling, wound healing in cell and tissue injuries, and cell differentiation via mechanisms that have yet to be fully understood.
TB-500 is a synthetic form of Thymosin Beta-4, a naturally occurring peptide present in virtually all animal cells. This powerful peptide is a member of a family of 16 related molecules found in most tissues and circulating cells in the body. TB-500 binds to actin, a cell-building protein, it also blocks actin polymerization.
Studies have shown that TB-500 is a potent wound repair factor with anti-inflammatory properties which occurs naturally. Thymosin Beta 4 is a little different from other repair factors, like growth factors, in that it will promote endothelial and keratinocyte migration. It also doesn't bind to the extracellular matrix and having a very low molecular weight means it can travel relatively long distances through tissues.
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