Description
Ostarine (MK-2866), a selective androgen receptor modulator (SARM), has been investigated in various animal studies for its effects on muscle growth, bone density, and metabolic health. Here are some key findings:
1. Muscle Growth and Wasting Prevention
Rodent Studies:
- - Ostarine significantly increased lean muscle mass in rats and mice, similar to anabolic steroids but with fewer side effects.
- - In muscle atrophy models, it helped prevent muscle wasting caused by glucocorticoids or neuromuscular diseases.
Mechanism:
- - It binds to androgen receptors, selectively stimulating muscle and bone tissue without affecting prostate or liver as much as traditional steroids.
2. Bone Density and Fracture Healing
Osteoporosis Models:
- - Animal studies showed that Ostarine increased bone mineral density and strength.
- - It stimulated osteoblast activity (bone-building cells) while inhibiting osteoclasts (bone breakdown).
- - It accelerated fracture healing in rodents.
3. Fat Loss and Metabolic Effects
Rodent Studies on Obesity & Diabetes:
- - Ostarine helped reduce fat mass while preserving lean tissue.
- - It improved insulin sensitivity and reduced blood glucose levels, making it promising for metabolic disorders.
